PRE-084 is a sigma receptor agonist, selective for the σ1 subtype. It has nootropic and antidepressant actions in animal studies, as well as antitussive and reinforcing effects.PRE-084 increases the expression of GDNF… High affinity, selective σ1 agonist (Ki values are 2.2 and 13091 nM for σ1 and σ2 receptors respectively). Selective over PCP receptors (IC50 > 100000 nM) and several other receptor systems. Produces antiamnesic and antitussive effects in vivo. Also exhibits protective effects in PC6.3 cells expressing mutant huntingtin by activating NF-κB signaling. This product is intended for laboratory research purposes only and are not to be used for any other purposes.
- Formula Name: 2-morpholin-4-ylethyl 1-phenylcyclohexane-1-carboxylate
- CAS: 138847-85-5
- Formula: C19H27NO3.HCl
- Molecular weight:353.89
- Compound purity:99 %
- Synonyms: 2-morpholin-4-ylethyl 1-phenylcyclohexane-1-carboxylate
- Minimum Quantity Order 20g